Nobiletin mitigates hepatocytes death, liver inflammation, and fibrosis in a murine model of NASH through modulating hepatic oxidative stress and mitochondrial dysfunction
Shuyu Li, Xi Li, Fangyuan Chen, Min Liu, Liuxin Ning, Yu-Feng Yan, Shuncai Zhang, Shaoping Huang, Chuantao Tu
Topics & Concepts
HepatocyteOxidative stressFibrosisLipotoxicityEndocrinologySteatosisHepatic stellate cellReactive oxygen speciesInternal medicineLipid peroxidationNobiletinSteatohepatitisBiologyChemistryFatty liverCell biologyMedicineBiochemistryInsulin resistanceInsulinAntioxidantIn vitroDiseaseFlavonoidBioactive Compounds in PlantsSesame and Sesamin ResearchLiver Disease Diagnosis and Treatment