Analyzing the potential targets and mechanism of per- and polyfluoroalkyl substances (PFAS) on breast cancer by integrating network toxicology, single-cell sequencing, spatial transcriptomics, and molecular simulation
Jiajun Li, Deqi Wang, Sihan Song, Yi Wang, Xinlei Wu, Zepeng Du, Yanggang Hong
Topics & Concepts
BiologyComputational biologyMechanism (biology)TranscriptomeBreast cancerBioinformaticsCancerToxicologyGeneticsGeneGene expressionEpistemologyPhilosophyPer- and polyfluoroalkyl substances researchAtmospheric chemistry and aerosolsFluorine in Organic Chemistry