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Simultaneous High-Purity Enantiomeric Resolution of Conglomerates Using Magnetic Substrates

Deb Kumar Bhowmick, Yutao Sang, Kakali Santra, Maximilian Halbauer, Eyal Capua, Yossi Paltiel, Ron Naaman, Francesco Tassinari

2021Crystal Growth & Design27 citationsDOIOpen Access PDF

Abstract

Applying magnetic substrates, magnetized perpendicular to the surface, we were able to crystallize from racemic solution pure conglomerates of several molecules. The resolution is based on the spin-dependent charge reorganization (SDCR) effect. By having two surfaces with opposite magnetization, it was possible to simultaneously crystallize on each surface a different enantiomer. The method does not require any seeding or chemical modification and is generally employable to any conglomerate. A system is presented for performing the separation, while the racemic mixture flows between the two magnetic surfaces.

Topics & Concepts

EnantiomerMagnetizationChemistryRacemic mixtureResolution (logic)MoleculeConglomeratePerpendicularCrystallographyAnalytical Chemistry (journal)StereochemistryMagnetic fieldOrganic chemistryGeometryArtificial intelligenceBiologySedimentary rockQuantum mechanicsPhysicsComputer scienceMathematicsPaleontologyOrigins and Evolution of LifeSpectroscopy and Quantum Chemical StudiesTheoretical and Computational Physics