Pre-lymphodepletion & infusion endothelial activation and stress index as predictors of clinical outcomes in CAR-T therapy for B-cell lymphoma
Aldo A. Acosta‐Medina, Isla McKerrow Johnson, Radhika Bansal, Matthew Hathcock, Saad S. Kenderian, Urshila Durani, Arushi Khurana, Yucai Wang, Jonas Paludo, José C. Villasboas, N. Nora Bennani, Patrick B. Johnston, Stephen M. Ansell, Yi Lin, Hassan B. Alkhateeb
Abstract
Chimeric antigen receptor T cell (CAR-T) therapy has been standard of care for multiple hematologic malignancies in the past few years. However, CAR-T-related toxicities remain a significant barrier limiting its efficacy [ 1 ].
Topics & Concepts
LymphomaMedicineInternal medicineIndex (typography)ImmunologyOncologyComputer scienceWorld Wide WebCAR-T cell therapy research