Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus
Claire Leibler, Shinu John, Rebecca A. Elsner, Kayla Thomas, Shuchi Smita, Stephen Joachim, Russell C. Levack, Derrick Callahan, Rachael A. Gordon, Sheldon Bastacky, Ryutaro Fukui, Kensuke Miyake, Sébastien Gingras, Kevin M. Nickerson, Mark J. Shlomchik
Topics & Concepts
TLR9Proinflammatory cytokineSystemic lupus erythematosusBiologyImmunologyGeneGeneticsInflammationComputational biologyMedicineGene expressionPathologyDiseaseDNA methylationImmune Response and Inflammationinterferon and immune responsesCytokine Signaling Pathways and Interactions