Cervical Squamous Intraepithelial Lesions Are Associated with Differences in the Vaginal Microbiota of Mexican Women
Miriam Nieves, Oswaldo Partida‐Rodríguez, Patricia Morán, Angélica Serrano-Vázquez, Horacio Pérez-Juárez, Martha Pérez‐Rodríguez, Marie‐Claire Arrieta, C. Ximénez-García, B. Brett Finlay
Abstract
Human papillomavirus (HPV) plays a critical role in cervical carcinogenesis but is not sufficient for cervical cancer development, indicating the involvement of other factors. The vaginal microbiota is an important factor in controlling infections caused by HPV, and, depending on its composition, it can modulate the microenvironment in vaginal mucosa against viral infections.
Topics & Concepts
MedicineSquamous intraepithelial lesionGynecologyCervical intraepithelial neoplasiaCervical cancerInternal medicineCancerReproductive tract infections researchCervical Cancer and HPV ResearchPelvic floor disorders treatments