S. cerevisiae Cells Can Grow without the Pds5 Cohesin Subunit
Karan Choudhary, Ziv Itzkovich, Elisa Alonso‐Perez, Hend Bishara, Barbara Dunn, Gavin Sherlock, Martin Kupiec
Abstract
Sister chromatid cohesion is vital for faithful chromosome segregation, chromosome folding into loops, and gene expression. A multisubunit protein complex known as cohesin holds the sister chromatids from S phase until the anaphase stage.
Topics & Concepts
CohesinEstablishment of sister chromatid cohesionSeparaseSister chromatidsAnaphaseChromosome segregationKinetochoreChromatidCell biologyGeneticsBiologyChromosomeProtein subunitGeneGenomics and Chromatin DynamicsPlant Molecular Biology ResearchMicrotubule and mitosis dynamics