Litcius/Paper detail

Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy

Chirag Krishna, Renzo G. DiNatale, Fengshen Kuo, Raghvendra M. Srivastava, Lynda Vuong, Diego Chowell, Sounak Gupta, Chad Vanderbilt, Tanaya A. Purohit, Ming Liu, Emily R. Kansler, Briana G. Nixon, Ying‐Bei Chen, Vladimir Makarov, Kyle A. Blum, Kyrollis Attalla, Stanley Weng, Michael Salmans, Mahdi Golkaram, Li Liu, Shile Zhang, Raakhee Vijayaraghavan, Traci Pawlowski, Victor E. Reuter, Maria I. Carlo, Martin H. Voss, Jonathan Coleman, Paul Russo, Robert J. Motzer, Ming O. Li, Christina S. Leslie, Timothy A. Chan, A. Ari Hakimi

2021Cancer Cell440 citationsDOIOpen Access PDF

Topics & Concepts

Immune checkpointImmune systemClear cell renal cell carcinomaCancer researchT cellCellT-cell receptorBiologyLymph nodeImmunotherapyTumor microenvironmentCell therapyMedicineImmunologyOncologyRenal cell carcinomaGeneticsSingle-cell and spatial transcriptomicsCancer Immunotherapy and BiomarkersRenal cell carcinoma treatment