A Single-Blinded Randomized Controlled Trial of Mesenchymal Stem Cell Therapy for the Treatment of Osteoarthritis of the Knee with Active Control
Joseph J Ruane, Andrew Ross, Victoria Zigmont, Deanna McClure, Gregg Gascon
Abstract
: Results demonstrate that both treatment groups experienced clinically and statistically significant improvement across the KOOS subscales. While BMAC has shown promise in the treatment of knee OA, there is a need for multi-center investigations with larger sample sizes, an extended follow-up, and placebo-based control. ClinicalTrials.gov Identifier: NCT02958267.
Topics & Concepts
OsteoarthritisRandomized controlled trialMedicineMesenchymal stem cellPhysical therapyAlternative medicineSurgeryPathologyOsteoarthritis Treatment and MechanismsTotal Knee Arthroplasty OutcomesPeriodontal Regeneration and Treatments