Se-methylselenocysteine ameliorates mitochondrial function by targeting both mitophagy and autophagy in the mouse model of Alzheimer's disease
Yongli Xie, Xiaoshan Ke, Z. Ye, Xuexia Li, Zetao Chen, Jiantao Liu, Ziyi Wu, Qiong Liu, Xiubo Du
Abstract
: This research indicated that SMC might exert its therapeutic effect by protecting mitochondria in 3 × Tg-AD mice.
Topics & Concepts
MitophagyAutophagyFunction (biology)Cell biologyMitochondrionChemistryPINK1BiologyBiochemistryApoptosisSelenium in Biological SystemsAlzheimer's disease research and treatmentsOrganoselenium and organotellurium chemistry