Nicotine‐based ionic liquid supported on magnetic nanoparticles: An efficient and recyclable catalyst for selective one‐pot synthesis of <i>mono</i>‐ and <i>bis</i>‐4<i>H</i>‐pyrimido[2,1‐<i>b</i>]benzothiazoles
Nasrin Alishahi, Mahboobeh Nasr‐Esfahani, Iraj Mohammadpoor‐Baltork, Shahram Tangestaninejad, Valiollah Mirkhani, Majid Moghadam
Abstract
In this study, an acidic nicotine‐based ionic liquid supported on magnetic nanoparticles ([NicTC]HSO 4 @MNPs) was synthesized and characterized by different techniques. The activity of this catalyst was evaluated in a multi‐component reaction of 2‐aminobenzothiazole , aldehydes / dialdehydes and β‐ketoesters/1,3‐diketones to afford a series of novel mono ‐ and bis ‐4 H ‐pyrimido[2,1‐ b ]benzothiazole derivatives. In addition, mild reaction conditions, high yields, excellent selectivity as well as easy recovery and reusability of the catalyst, make this method an economic and environmentally‐benign process.
Topics & Concepts
ChemistryBenzothiazoleIonic liquidCatalysisReusabilitySelectivityMagnetic nanoparticlesNanoparticleCombinatorial chemistryIonic bondingOrganic chemistryNuclear chemistryChemical engineeringIonComputer scienceSoftwareEngineeringProgramming languageMulticomponent Synthesis of HeterocyclesSynthesis and Biological EvaluationSynthesis and biological activity