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Solid–Liquid Equilibrium Behavior and Solvent Effect of Gliclazide in Mono- and Binary Solvents

Zihao Wang, Shuai Yu, Hongcheng Li, Bin Liu, Yan Xia, Jianhui Guo, Fumin Xue

2022ACS Omega12 citationsDOIOpen Access PDF

Abstract

model, the Yaws model, the Apelblat model, the Jouyban model, the modified Jouyban-Acree model, and the Sun model). The results show that all of these models can correlate the experimental data well. Among them, the Apelblat model is the most suitable for correlating the solubility data of gliclazide in mono-solvents and binary solvents.

Topics & Concepts

SolubilityChemistryGravimetric analysisSolvent1,2-DichloroethaneIsopropyl alcoholGliclazideOrganic chemistryThermodynamicsCatalysisEndocrinologyMedicinePhysicsInsulinCrystallization and Solubility StudiesChemical and Physical Properties in Aqueous SolutionsAnalytical Chemistry and Chromatography