Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress
Anish Thomas, Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli, Kelli M. Wilson, Yang Zhang, Erin Beck, Linda Sciuto, Samantha Nichols, Brian Elenbaas, Janusz Puc, Heike Dahmen, Astrid Zimmermann, Jillian Varonin, Christopher W. Schultz, Se Hyun Kim, Hirity Shimellis, Parth Desai, Carleen Klumpp‐Thomas, Lu Chen, Jameson Travers, Crystal McKnight, Sam Michael, Zina Itkin, Sunmin Lee, Akira Yuno, Min-Jung Lee, Christophe E. Redon, Jessica D. Kindrick, Cody J. Peer, Jun S. Wei, Mirit I. Aladjem, William D. Figg, Seth M. Steinberg, Jane B. Trepel, Frank T. Zenke, Yves Pommier, Javed Khan, Craig J. Thomas
Topics & Concepts
Cancer researchTopotecanGenome instabilityTopoisomeraseBiologyOncologyMedicineImmunologyInternal medicineDNA damageGeneticsChemotherapyDNALung Cancer Research StudiesNeuroendocrine Tumor Research AdvancesCancer therapeutics and mechanisms