Litcius/Paper detail

Ni-catalyzed regioselective and site-divergent reductive arylalkylations of allylic amines

Huan Meng, Jun-Song Jia, Pengfei Yang, Yulong Li, Qiong Yu, Wei Shu

2025Chemical Science13 citationsDOIOpen Access PDF

Abstract

A Ni-catalyzed cross-electrophile regioselective and site-divergent 1,2- and 1,3-arylalkylations of allylic amines has been developed, representing the first controllable migratory difunctionalization of alkenes under reductive conditions.

Topics & Concepts

RegioselectivityAllylic rearrangementCatalysisChemistryCombinatorial chemistryStereochemistryOrganic chemistryCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsAsymmetric Hydrogenation and Catalysis