Multi-targeting TACE/ADAM17 and gamma-secretase of notch signalling pathway in TNBC via drug repurposing approach using Lomitapide
Plaboni Sen, Thirukumaran Kandasamy, Siddhartha Sankar Ghosh
Topics & Concepts
Notch signaling pathwayProteasesCancer researchDownregulation and upregulationGamma secretaseAmyloid precursor protein secretaseBiologyCell biologySignal transductionMedicineInternal medicineBiochemistryEnzymeGeneDiseaseAmyloid precursor proteinAlzheimer's diseaseHistone Deacetylase Inhibitors ResearchCancer-related gene regulationCytokine Signaling Pathways and Interactions