DHEA-S production capacity in relation to perceived prolonged stress
Anna-Karin Lennartsson, Elin Arvidson, Mats Börjesson, Ingibjörg H. Jónsdóttir
Abstract
= 36) according their response to a single question regarding perceived stress during the preceding month. They underwent the Trier Social Stress Test while blood samples were drawn before, during and after the stress test. The concentration of DHEA, DHEA-S, cortisol and ACTH was measured. The results showed that the high stress group exhibited a significantly lower response of DHEA-S (40% lower) than the low stress group, while DHEA, cortisol and ACTH responses did not differ between the groups. Reduced DHEA-S production may constitute one of the links between stress and poor health.
Topics & Concepts
Trier social stress testDehydroepiandrosteroneDehydroepiandrosterone sulfateChronic stressPsychologyEndocrinologyInternal medicineAnabolismHormoneMedicineStress (linguistics)Fight-or-flight responseAndrogenChemistryPhilosophyLinguisticsBiochemistryGeneHormonal and reproductive studiesStress Responses and CortisolHormonal Regulation and Hypertension