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Risk of Mucormycosis in Diabetes Mellitus: A Systematic Review

Manish Khanna, Sabitha Challa, Ahmed S Kabeil, Bithaiah Inyang, Faisal J Gondal, Godwin A Abah, Mahesh Minnal Dhandapani, Manasa Manne, Lubna Mohammed

2021Cureus47 citationsDOIOpen Access PDF

Abstract

Hyperglycemia or diabetes mellitus (DM) is a disorder of the endocrine system. In this condition, the body is insulin-deficient or resistant to insulin. Due to insulin deficiency or resistance, the body is unable to process sugar. The worldwide prevalence of diabetes mellitus is rising substantially. Hyperglycemia makes the immune system weak, which increases the risk of infection in a diabetic patient. Fungal infection is more common in DM. Mucormycosis is a rare fungal infection in a healthy individual, but in DM, it can cause severe complications and even be fatal if not treated adequately and timely. In our literature review, a total of 19 published articles from the PubMed database and Google Scholar were included. We combed the PubMed database and Google Scholar by using various inclusion and exclusion criteria. The result of the review study shows the increased risk of mucormycosis in a diabetic patient.

Topics & Concepts

MedicineMucormycosisDiabetes mellitusInsulin resistanceEndocrine systemIntensive care medicineInclusion and exclusion criteriaInsulinInternal medicineSurgeryEndocrinologyPathologyHormoneAlternative medicineAntifungal resistance and susceptibilityNatural Antidiabetic Agents Studies
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