Multivessel Coronary Artery Disease

Abstract

Multivessel coronary artery disease (MVD) is defined as luminal stenosis of at least 70% in at least two major coronary arteries or in one coronary artery in addition to a 50% or greater stenosis of the left main trunk. It is both common and deadly: 45% to 88% of men with angina have MVD, which carries a mortality hazard ratio of 3.14 compared to single-vessel disease.1,2 Given that percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) both effectively revascularize the myocardium, there has been ardent study of and debate over the optimal revascularization strategy for patients with MVD.

Topics & Concepts