Metformin ameliorates doxorubicin-induced cardiotoxicity targeting HMGB1/TLR4/NLRP3 signaling pathway in mice
Amany A. Alzokaky, Ahmed A. Al‐Karmalawy, Mohamed A. Saleh, Walied Abdo, Amira E. Farage, Amany Belal, Mohammed A. S. Abourehab, Samar A. Antar
Topics & Concepts
CardiotoxicityHMGB1PharmacologyInflammasomeMalondialdehydeMetforminDoxorubicinOxidative stressSuperoxide dismutaseInflammationChemistryMedicineToxicityBiochemistryInternal medicineEndocrinologyChemotherapyDiabetes mellitusChemotherapy-induced cardiotoxicity and mitigationChemotherapy-induced organ toxicity mitigationLung Cancer Research Studies