Targeting the DNA damage response: PARP inhibitors and new perspectives in the landscape of cancer treatment
Sofia Genta, Federica Martorana, Anastasios Stathis, Ilaria Colombo
Topics & Concepts
Poly ADP ribose polymeraseCarcinogenesisDNA repairDNA damageHomologous recombinationSynthetic lethalityCancer researchPARP inhibitorCancerBiologyPopulationBiomarkerMedicineComputational biologyBioinformaticsPolymeraseDNAGeneticsEnvironmental healthPARP inhibition in cancer therapyDNA Repair MechanismsLow-power high-performance VLSI design