Brain-derived neurotrophic factor (BDNF) activates PI3K-AKT-mTOR signaling via hypothalamic TrkB receptors to reduce feeding in Siberian sturgeon (Acipenser baerii)
Shupeng Zhang, Yongpei Lu, Yingzi Li, Yan‐Ling Liu, Qin Yao, Qin Kang, Shu‐Huang Chen, Youlian Liu, Yixiao Xiong, Defang Chen, Xin Zhang, Ni Tang, Zhiqiong Li
Topics & Concepts
Tropomyosin receptor kinase BBiologyEndocrinologyInternal medicineBrain-derived neurotrophic factorSturgeonOrexigenicDownregulation and upregulationNeurotrophic factorsHypothalamusLeptinLeptin receptorProtein kinase BPI3K/AKT/mTOR pathwayNeurotrophinReceptorCell biologySignal transductionNeuropeptide Y receptorNeuropeptideFisheryMedicineBiochemistryGeneFish <Actinopterygii>ObesityNerve injury and regenerationCardiovascular, Neuropeptides, and Oxidative Stress ResearchNeurogenesis and neuroplasticity mechanisms