Secukinumab alleviates cognitive impairment by attenuating oxidative stress and neuronal apoptosis via the IL-17RA/AKT/ERK1/2 pathway in a rat model of sepsis
Jiamin Gao, Yiduo Wang, Senlin Ma, Siyuan Xu, Mingquan Chen
Topics & Concepts
Morris water navigation taskMedicineOxidative stressIntraperitoneal injectionSepsisHippocampusProtein kinase BAnesthesiaInternal medicinePharmacologyEndocrinologyApoptosisImmunologyBiologyBiochemistryIntensive Care Unit Cognitive DisordersSepsis Diagnosis and TreatmentImmune Response and Inflammation