Rationale for IL-15 superagonists in cancer immunotherapy
Karin M. Knudson, James W. Hodge, Jeffrey Schlom, Sofia R. Gameiro
Abstract
Interleukin (IL)-15 (IL-15) is a promising cytokine for the treatment of hematological and solid malignancies. It is a member of the common receptor gamma chain (γc) family, which also includes IL-...
Topics & Concepts
ImmunotherapyMedicineCommon gamma chainCytokineCancer immunotherapyCancerImmunologyCancer researchInternal medicineInterleukin 10Immune Cell Function and InteractionT-cell and B-cell ImmunologyToxin Mechanisms and Immunotoxins