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Identification of a Novel Ciprofloxacin Tolerance Gene, <i>aciT</i> , Which Contributes to Filamentation in Acinetobacter baumannii

Varsha Naidu, Bhumika S. Shah, Karthik Shantharam Kamath, Arthur Chien, Stephanie Nagy, Alaska Pokhrel, Mark P. Molloy, Karl A. Hassan, Ian T. Paulsen

2021Antimicrobial Agents and Chemotherapy18 citationsDOIOpen Access PDF

Abstract

species, suggesting an important role. With these findings taken together, this study has identified a new gene conferring tolerance to ciprofloxacin, likely by enabling filamentation in response to the antibiotic.

Topics & Concepts

Acinetobacter baumanniiFilamentationCiprofloxacinAcinetobacterMicrobiologyBiologyAntibioticsPseudomonas aeruginosaGeneticsBacteriaLaserOpticsPhysicsAntibiotic Resistance in BacteriaCancer therapeutics and mechanismsBacterial Genetics and Biotechnology
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