Electrochemical sensing technology based on a ligation-initiated LAMP-assisted CRISPR/Cas12a system for high-specificity detection of EGFR E746–A750 deletion mutation
Cizhi Chen, Siyu Chen, Yang Fu, Yuxin Wei, Linzhi Xie, Mei Chen, Linzhi Xie, Mei Chen
Topics & Concepts
CRISPRLoop-mediated isothermal amplificationEpidermal growth factor receptorComputational biologyPoint mutationBiologyDNAComputer scienceMutationNanotechnologyMaterials scienceGeneticsGeneCancerAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringBiosensors and Analytical Detection