Thrombospondin-1 promotes mechanical stress-mediated ligamentum flavum hypertrophy through the TGFβ1/Smad3 signaling pathway
Run Zhao, Jiale Dong, Chunlei Liu, Mingheng Li, Ruiqian Tan, Chengshuo Fei, Yanlin Chen, Xinxing Yang, Jiawei Shi, Jiajia Xu, Liang Wang, Peng Li, Zhongmin Zhang
Topics & Concepts
Transforming growth factorFibrosisThrombospondinThrombospondin 1Muscle hypertrophySignal transductionCell biologyMedicineCancer researchPathologyInternal medicineBiologyMetalloproteinaseMatrix metalloproteinaseAngiogenesisSpine and Intervertebral Disc PathologyCervical and Thoracic MyelopathyTGF-β signaling in diseases