Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
Till Ringel, Nina Frey, Femke Ringnalda, Sharan Janjuha, Sarah Cherkaoui, Stefan Butz, Sumana Srivatsa, Martin Pirkl, Giancarlo Russo, Lukas Villiger, Gerhard Rogler, Hans Clevers, Niko Beerenwinkel, Nicola Zamboni, Tuncay Baubec, Gerald Schwank
Topics & Concepts
BiologyOrganoidCRISPRGenomeComputational biologyScale (ratio)Transforming growth factorGeneticsGeneCell biologyQuantum mechanicsPhysicsCRISPR and Genetic EngineeringMycobacterium research and diagnosis