In vivo CART cell imaging: Paving the way for success in CART cell therapy
Reona Sakemura, İsmail Can, Elizabeth L. Siegler, Saad S. Kenderian
Abstract
, including nonspecific strategies to image activated T cells and reporter systems to specifically detect engineered T cells. Many of these platforms are clinically applicable and hold promise to provide valuable information and guide improved CART cell treatment.
Topics & Concepts
CartChimeric antigen receptorImmunotherapyCellIn vivoCell therapyMedicineT cellImmune systemCancer researchBiologyImmunologyGeneticsMechanical engineeringBiotechnologyEngineeringCAR-T cell therapy researchVirus-based gene therapy researchNanowire Synthesis and Applications