Psychiatric comorbidities in adults with sickle cell disease: A narrative review
Adrienne D. Mishkin, Elizabeth Prince, Elizabeth J. Leimbach, Markus Y. Mapara, C. Patrick Carroll
Abstract
Although descriptions of quality of life and patient reports of mood in sickle cell disease (SCD) have become more common in the literature, less is known about psychiatric illness prevalence, presentation, and treatment, particularly for adults. We provide a narrative review of what is known about common and debilitating psychiatric conditions such as depression, anxiety, and cognitive impairment, specifically for adults with SCD. We discuss the limitations of the current evidence, make provisional recommendations, and identify opportunities for research and improved care.
Topics & Concepts
Depression (economics)AnxietyDiseaseMoodMedicineQuality of life (healthcare)PsychiatryNarrative reviewPresentation (obstetrics)CognitionClinical psychologyIntensive care medicineInternal medicineRadiologyNursingMacroeconomicsEconomicsHemoglobinopathies and Related DisordersIron Metabolism and DisordersPharmacological Effects and Toxicity Studies