Capsaicin ameliorates intermittent high glucose-mediated endothelial senescence via the TRPV1/SIRT1 pathway
Si-Lu Zhu, Meiling Wang, Yue-Teng He, Shu-Wen Guo, Tingting Li, Weijie Peng, Dan Luo
Topics & Concepts
SenescenceAMPKCapsaicinTRPV1ChemistryReactive oxygen speciesCell biologyCell cycle checkpointOxidative stressDownregulation and upregulationPharmacologyApoptosisCell cycleMedicineBiologyBiochemistryPhosphorylationReceptorProtein kinase ATransient receptor potential channelGeneIon Channels and ReceptorsTelomeres, Telomerase, and SenescenceSirtuins and Resveratrol in Medicine