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Recent progress towards catalytic asymmetric construction of inherently chiral scaffolds

Kai Zhu, David R. Spring, Bing‐Feng Shi, Fengzhi Zhang

2025Chemical Society Reviews8 citationsDOIOpen Access PDF

Abstract

]arenes, saddle-shaped scaffolds, mechanically interlocked molecules, and prism-like cages under catalyst control, which would offer valuable insights for future research on the rational design of conceptually novel and streamlined asymmetric synthetic systems, thereby expanding the scope/chemical space and improving the added value of inherently chiral molecules.

Topics & Concepts

Enantioselective synthesisNanotechnologyRational designCatalysisBiochemical engineeringCombinatorial chemistryChirality (physics)Materials scienceChemistryComputer scienceDesign elements and principlesAsymmetric hydrogenationSurface Chemistry and CatalysisAxial and Atropisomeric Chirality SynthesisAsymmetric Hydrogenation and Catalysis
Recent progress towards catalytic asymmetric construction of inherently chiral scaffolds | Litcius