A selective NLRP3 inflammasome inhibitor attenuates behavioral deficits and neuroinflammation in a mouse model of Parkinson's disease
Shuxuan Huang, Zhi Chen, Binglin Fan, Yuan Chen, Liyuan Zhou, Bingjian Jiang, Haiyin Long, Weizhang Zhong, Xiaofeng Li, Yànhuá Lǐ
Topics & Concepts
InflammasomeMPTPNeuroprotectionNeuroinflammationDopaminergicAIM2Parkinson's diseaseNeurosciencePharmacologyNLRC4Substantia nigraMedicineReceptorCaspase 1ChemistryBiologyImmunologyDopamineInternal medicineInflammationDiseaseRestless Legs Syndrome ResearchParkinson's Disease Mechanisms and TreatmentsInflammasome and immune disorders