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Mouse models of neutropenia reveal progenitor-stage-specific defects

David E. Muench, André Olsson, Kyle Ferchen, Giang Pham, Rachel A. Serafin, Somchai Chutipongtanate, Pankaj Dwivedi, Baobao Song, Stuart Hay, Kashish Chetal, L. Trump-Durbin, Jayati Mookerjee‐Basu, Kejian Zhang, Jennifer C. Yu, Carolyn Lutzko, Kasiani C. Myers, Kristopher L. Nazor, Kenneth D. Greis, Dietmar J. Kappes, Sing Sing Way, Nathan Salomonis, H. Leighton Grimes

2020Nature114 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCongenital NeutropeniaGeneticsEpigeneticsGeneProgenitor cellForward geneticsTranscription factorNeutropeniaLocus (genetics)MutantMutationStem cellChemotherapyBlood disorders and treatmentsImmunodeficiency and Autoimmune DisordersErythrocyte Function and Pathophysiology
Mouse models of neutropenia reveal progenitor-stage-specific defects | Litcius