Wound Repair and Ca2+ Signalling Interplay: The Role of Ca2+ Channels in Skin
Gregorio Bonsignore, Simona Martinotti, Elia Ranzato
Abstract
The process of wound healing is intricate and tightly controlled, involving a number of different cellular and molecular processes. Numerous cellular functions, especially those related to wound healing, depend critically on calcium ions (Ca2+). Ca2+ channels are proteins involved in signal transduction and communication inside cells that allow calcium ions to pass through cell membranes. Key Ca2+ channel types involved in wound repair are described in this review.
Topics & Concepts
Wound healingCalcium signalingIon channelCell biologyCalciumSignal transductionChemistryCell signalingTransduction (biophysics)MembraneVoltage-dependent calcium channelBiophysicsBiologyBiochemistryReceptorImmunologyOrganic chemistryIon Channels and ReceptorsPlant Stress Responses and ToleranceWound Healing and Treatments