Clinical evaluation of a low-coverage whole-genome test for detecting homologous recombination deficiency in ovarian cancer
Romain Boidot, Michaël G. B. Blum, Marie-Pierre Wissler, Céline Gottin, Jiří Růžička, Sandy Chevrier, Tiffany M. Delhomme, Jérôme Audoux, Adrien Jeanniard, Pierre‐Alexandre Just, Philipp Harter, Sandro Pignata, Antonio González-Martı́n, Christian Marth, Johanna Mäenpää, Nicoletta Colombo, Ignace Vergote, Keiichi Fujiwara, Nicolas Duforet-Frebourg, Denis Bertrand, Nicolas Philippe, Isabelle Ray‐Coquard, Éric Pujade-Lauraine
Topics & Concepts
OlaparibOvarian cancerMedicineConcordanceBevacizumabHazard ratioInternal medicineOncologyConfidence intervalHomologous recombinationCancerClinical trialChemotherapyGeneBiologyGeneticsPolymerasePoly ADP ribose polymerasePARP inhibition in cancer therapyDNA Repair MechanismsBRCA gene mutations in cancer