Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors
Sanaz Darbalaei, Elita Yuliantie, Antao Dai, Rulue Chang, Peishen Zhao, Dehua Yang, Ming-Wei Wang, Patrick M. Sexton, Denise Wootten
Topics & Concepts
Functional selectivityGlucagon receptorReceptorG protein-coupled receptorPharmacologyGlucagon-like peptide-1AgonistGlucagon-like peptide 1 receptorChemistryGlucagonEndocrinologyBiologyDiabetes mellitusInsulinType 2 diabetesBiochemistryDiabetes Treatment and ManagementReceptor Mechanisms and SignalingNeuropeptides and Animal Physiology