Novel deuterated Mnk1/2 protein degrader VNLG-152R analogs: Synthesis, In vitro Anti-TNBC activities and pharmacokinetics in mice
Puranik Purushottamachar, Elizabeth Thomas, Retheesh S. Thankan, Vincent C.O. Njar
Topics & Concepts
ChemistryPharmacokineticsPharmacologyIn vitroPaclitaxelCyclin D1Cancer researchBiochemistryCellCell cycleInternal medicineChemotherapyBiologyMedicineChemical Reactions and IsotopesPharmacogenetics and Drug MetabolismAmino Acid Enzymes and Metabolism