Intracellular immune sensing promotes inflammation via gasdermin D–driven release of a lectin alarmin
Ashley J. Russo, Swathy O. Vasudevan, Santiago P. Méndez‐Huergo, P. Hima Kumari, Antoine Ménoret, Shivalee Duduskar, Chengliang Wang, Juan M. Pérez Sáez, Margaret M. Fettis, Chuan Li, Renjie Liu, Arun Wanchoo, Karthik Chandiran, Jianbin Ruan, Sivapriya Kailasan Vanaja, Michael Bauer, Christoph Sponholz, Gregory A. Hudalla, Anthony T. Vella, Beiyan Zhou, Sachin D. Deshmukh, Gabriel A. Rabinovich, Vijay Rathinam
Topics & Concepts
PyroptosisNecroptosisInflammationGalectin-1Galectin-3Cell biologyGalectinProgrammed cell deathLipopolysaccharideProinflammatory cytokineCytosolBiologyIntracellularImmune systemImmunologyApoptosisInflammasomeBiochemistryEnzymeInflammasome and immune disordersGalectins and Cancer BiologyAmoebic Infections and Treatments