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Tracing oncogene-driven remodelling of the intestinal stem cell niche

Min Kyu Yum, Seungmin Han, Juergen Fink, Szu-Hsien Sam Wu, Catherine Dabrowska, Teodora Trendafilova, Roxana C. Mustata, Lemonia Chatzeli, Roberta Azzarelli, Irina Pshenichnaya, Eunmin Lee, Frances J. England, Jong Kim, Daniel E. Stange, Anna Philpott, Joo‐Hyeon Lee, Bon‐Kyoung Koo, Benjamin D. Simons

2021Nature112 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCell biologyWnt signaling pathwayStem cellStromal cellNicheMutantKRASCancer researchGeneticsSignal transductionMutationGeneEcologyHippo pathway signaling and YAP/TAZCancer Cells and MetastasisPI3K/AKT/mTOR signaling in cancer
Tracing oncogene-driven remodelling of the intestinal stem cell niche | Litcius