Visible-light-mediated C–F bond cleavage for the synthesis of polyfluorinated compounds
Bin Wang, Cui‐Tian Wang, Xuesong Li, Wenhui Sun, Xue‐Yuan Liu, Yong‐Min Liang
Abstract
Herein, we describe a novel and efficient photo-redox catalytic difluorinated ester radical addition/defluoroalkylation coupling reaction between trifluoroacetic acid derivatives and α-trifluoromethyl alkenes.
Topics & Concepts
ChemistryTrifluoroacetic acidTrifluoromethylCatalysisCleavage (geology)Bond cleavageRedoxMedicinal chemistryVisible spectrumCombinatorial chemistryPhotochemistryOrganic chemistryPhysicsEngineeringOptoelectronicsAlkylGeotechnical engineeringFracture (geology)Fluorine in Organic ChemistryRadical Photochemical ReactionsSulfur-Based Synthesis Techniques