Litcius/Paper detail

Iridium(III)-BBIP complexes induce apoptosis via PI3K/AKT/mTOR pathway and inhibit A549 lung tumor growth in vivo

Yi Zhou, Lan Bai, Tian Li, Linlin Yang, Huiwen Zhang, Yuanyuan Zhang, Jing Hao, Yiying Gu, Yunjun Liu

2021Journal of Inorganic Biochemistry26 citationsDOI

Topics & Concepts

ChemistryPI3K/AKT/mTOR pathwayProtein kinase BApoptosisEndoplasmic reticulumMolecular biologyA549 cellHeLaCell growthCell cycleKinaseCell biologyBiochemistryCellBiologyQuinazolinone synthesis and applicationsSynthesis and bioactivity of alkaloidsCancer therapeutics and mechanisms