Chitin synthase: A potential agricultural and therapeutic target
Ying Ye, Ze-Wei Guan, Xiao‐Lei Zhu, Guang‐Fu Yang
Abstract
Chitin synthase (CHS) is a potential agricultural and therapeutic target. Recently, the crystal structures of CHS from Phytophthora sojae (PsChs1) and Candida albicans (CaChs2) were reported. Here, we highlight the achievements of PsChs1 and CaChs2, which would give some clues for design new inhibitor targeted upon CHS.
Topics & Concepts
ChitinCandida albicansChitin synthaseATP synthaseAntifungalBiologyMicrobiologyChemistryBiochemistryEnzymeChitosanPlant-Microbe Interactions and ImmunityStudies on Chitinases and ChitosanasesLegume Nitrogen Fixing Symbiosis