Cardamonin inhibits the progression of oesophageal cancer by inhibiting the PI3K/AKT signalling pathway
Zijie Wang, Hui Liu, Qing Hu, Lei Shi, Muhan Lü, Mingming Deng, Gang Luo
Abstract
In summary, CAR exhibited a strong anticancer effect on human oesophageal cancer cells and promoted apoptosis by inhibiting the PI3K/AKT signalling pathway, suggesting that CAR can be used as new strategy for oesophageal cancer treatment.
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BCancer researchSignalling pathwaysCancerMedicineSignallingSignal transductionBiologyInternal medicineCell biologyCancer-related gene regulationCancer-related Molecular PathwaysCancer-related molecular mechanisms research