Antiretroviral drug activity and potential for pre-exposure prophylaxis against COVID-19 and HIV infection
Dennis C. Copertino, Bruno C. Casado Lima, Rodrigo R. R. Duarte, Timothy R. Powell, Christopher E. Ormsby, Timothy Wilkin, Roy M. Gulick, Miguel de Mulder Rougvie, Douglas F. Nixon
Abstract
and in clinical trials. Further studies are needed to establish the activity of ARVs for treatment or prevention of SARS-CoV-2 infection .Communicated by Ramaswamy H. Sarma.
Topics & Concepts
AtazanavirRitonavirLopinavirIndinavirVirologyMedicinePharmacologyZidovudineEmtricitabineDrugNelfinavirAmprenavirProteaseBiologyHuman immunodeficiency virus (HIV)Viral loadViral diseaseEnzymeAntiretroviral therapyHIV-1 proteaseBiochemistrySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testing