2-Pyridone natural products as inhibitors of SARS-CoV-2 main protease
Katrina Forrestall, Darcy E. Burley, Meghan K. Cash, Ian R. Pottie, Sultan Darvesh
Topics & Concepts
PharmacophoreChemistryProteaseStereochemistryAutoDockLigand (biochemistry)Docking (animal)EnzymeActive siteMoietyCombinatorial chemistryIn silicoBiochemistryReceptorGeneNursingMedicineComputational Drug Discovery MethodsSARS-CoV-2 and COVID-19 ResearchSynthesis and biological activity