Identification of the Viral Determinant of Hypovirulence and Host Range in Sclerotiniaceae of a Genomovirus Reconstructed from the Plant Metagenome
Chenchen Feng, Jiuhuan Feng, Ziyi Wang, Connor Pedersen, Xiuqing Wang, Huma Saleem, Leslie L. Domier, Shin-Yi Lee Marzano
Abstract
. The viral determinant of hypovirulence was further identified as replication initiation protein. As a proof of concept, we demonstrate that viromes discovered in plant metagenomes can be a valuable genetic resource when novel viruses are rescued and characterized for their host range.
Topics & Concepts
BiologyMetagenomicsIdentification (biology)Host (biology)Computational biologyRange (aeronautics)Human viromeGeneticsVirologyEvolutionary biologyBotanyGeneMaterials scienceComposite materialPlant Virus Research StudiesPlant and Fungal Interactions ResearchPlant pathogens and resistance mechanisms