Visible light/copper catalysis enabled alkylation of silyl enol ethers with arylsulfonium salts
Wenwen Cui, Guoju Guo, Yifei Wang, Xiuyan Song, Jian Lv, Daoshan Yang
Abstract
An efficient protocol has been developed herein for the site-selective alkylation of silyl enol ethers with arylsulfonium salts giving access to valuable aryl alkyl thioethers under visible light conditions. Enabled by copper (I) photocatalysis, the C-S bond of arylsulfonium salts can be selectively cleaved to deliver C-centered radicals under mild conditions. This developed method provides a straightforward approach to utilize arylsulfonium salts as sulfur sources for the synthesis of aryl alkyl thioethers.
Topics & Concepts
EnolAlkylationSilylationAlkylChemistryArylCatalysisPhotocatalysisVisible spectrumCopperPhotoredox catalysisOrganic chemistrySulfurPhotochemistryCombinatorial chemistryMaterials scienceOptoelectronicsSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods