Litcius/Paper detail

Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements

Lovelace J. Luquette, Michael B. Miller, Zinan Zhou, Craig L. Bohrson, Yifan Zhao, Hu Jin, D. Gulhan, Javier Ganz, Sara Bizzotto, Samantha L. Kirkham, Tino Hochepied, Claude Libert, Alon Galor, Junho Kim, Michael A. Lodato, Juan I. Garaycoechea, Charles Gawad, Jay West, Christopher A. Walsh, Peter J. Park

2022Nature Genetics105 citationsDOIOpen Access PDF

Topics & Concepts

IndelBiologyGeneticsINDEL MutationSomatic cellPoint mutationGenomeDNA sequencingHuman genomeMutationGeneComputational biologyWhole genome sequencingSingle-nucleotide polymorphismGenotypeSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsCRISPR and Genetic Engineering