Prognostic value and potential molecular mechanism of the like-Sm gene family in early-stage pancreatic ductal adenocarcinoma
Zijun Chen, Chuangye Han, Xin Zhou, Xiangkun Wang, Xiwen Liao, Yongfei He, Shutian Mo, Xuan Li, Guangzhi Zhu, Xinping Ye, Tao Peng
Abstract
BACKGROUND: gene is known as GRP and YER112W. METHODS: genes are associated with RNA splicing, RNA synthesis, and RNA decomposition, and they may indirectly cause carcinogenesis through other genes such as myc. RESULTS: (adjusted HR =1.803) tended to experience bad outcomes. CONCLUSIONS: might be used as prognostic biomarkers in early PDAC.
Topics & Concepts
GenePancreatic cancerBiologyCancer researchCarcinogenesisRNAGene expressionTranscriptomeRNA splicingAlternative splicingProportional hazards modelMessenger RNACancerBioinformaticsOncologyInternal medicineGeneticsMedicinePancreatic and Hepatic Oncology ResearchGalectins and Cancer BiologyFerroptosis and cancer prognosis