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Unsupervised Learning Methods for Molecular Simulation Data

Aldo Glielmo, Brooke E. Husic, Álex Rodríguez, Cecilia Clementi, Frank Noé, Alessandro Laio

2021Chemical Reviews408 citationsDOIOpen Access PDF

Abstract

. We divide our discussion into self-contained sections, each discussing a specific method. In each section, we briefly touch upon the mathematical and algorithmic foundations of the method, highlight its strengths and limitations, and describe the specific ways in which it has been used-or can be used-to analyze molecular simulation data.

Topics & Concepts

Cluster analysisDimensionality reductionUnsupervised learningRepresentation (politics)Field (mathematics)Artificial intelligenceFeature (linguistics)Curse of dimensionalityComputer scienceChemistryMachine learningPure mathematicsPhilosophyPolitical scienceLinguisticsPoliticsLawMathematicsMachine Learning in Materials ScienceProtein Structure and DynamicsMetabolomics and Mass Spectrometry Studies
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